CoCl2 and NiCl2 are activators of haem oxygenase, the rate-limiting enzyme in haem catabolism. The effects of these metal ions on splenic and hepatic levels of ALA synthase and dehydratase as well as urinary levels of ALA and phosphobilinogen were also assayed. Both metals ions increased splenic expression of haem oxygenase 1 and iron regulated protein 1, proteins involved, respectively, in haem degradation and iron efflux. Keywords Aminolaevulinic acid synthase, cobalt, iron absorption, nickel.
Received Sep 6; Accepted Oct 1. This article has been cited by other articles in PMC.
The prepared complexes were characterized quantitatively and qualitatively by using: This triazole ligand act as bidentate that coordination to the metal ions through sulphur and amine group.
According to the spectral data of the complexes a tetrahedral geometry was suggested for these complexes except Cu II complexes which exhibit a square structure.
Triazole ring, Triazole complexes, Transition metal complexes Introduction Heterocyclic chemistry has now become a separate field of chemistry with long history, present society and future prospects. Nitrogen, oxygen and sulfur are considered the most hetero atoms known.
Heterocyclic compounds are considered one of an important type of organic compounds due to their implication in drugs and industrial studies CareyAcheson,Zamani et al. Triazoles are five memberd heterocyclic compounds with molecular formula C2H3N3 containing three nitrogen and two carbon atoms Siddiqui et al.
There are two types of triazole, the 1,2,3-triazoles and the 1,2,4-triazoles Bele and Singhvi,Clayden et al. Amine and thione-substituted triazoles have been studied as anti-inflammatory and anti-microbial agents and other applications Awad et al. Triazole are considered to be good coordinating ligands Al-Maydama et al.
This ligand have doner group that coordinate with wide range of metal ions Narayana and Gajendragad, The tatumerisum form could occur in triazole Davari et al.
The potential coordinating sites are: Thus this ligand is polydentate, it has been shown and experimentally verified that Complexes of polydentate ligands are called chelate complexes.
They tend to be more stable than complexes derived from monodentate ligands HartwigFurthermore five or six membered chelate is by far the most common and the most stable. A new thio- Triazole complexes with selected metals was prepared Majeed and Alabdeen, Materials and methods All the reagents, starting materials as well as solvents were purchased commercially and used without any further purification.
The melting points were recorded in Coslab melting point apparatus. The magnetic susceptibility values were obtained at room temperature using Magnetic Susceptibility Balance Johnson Matthey.
Conductivity measurements were carried out by using WTW conductivity meter. The salt was obtained in almost quantitative yield and was employed to the next step. After cooling the reaction mixture was filtered, and then was acidified by Hydrochloric acid to yield the white precipitate Siddiqui et al.
The resulting solids were washed by hot methanol and left to dried and recrystallized from ethanol Majeed et al. The data of CHNS and were obtained using flame atomic absorption technique.
The calculated values were in a good agreement with the experimental values. Table 1 Physical data of prepared complexes Complexes.All metals have certain common properties: they can be polished to a shiny luster, the conduct heat and electricity, are malleable and ductile, and in terms of chemical reactions, they will lose.
Concepts in Transition Metal Chemistry – Questions The compound is unstable with respect to the transition metal and a compound of higher oxidation state. Chapter 3 1Which of the ligands in the structures 1, 2 and 3 match(es) the descriptions below? sign and the metal ion is . The other major ion/ion reaction channel noted corresponds to reaction 2, which leads to transition-metal ion incorporation into the hexa-dA.
Note that a doubly charged product ion is also observed at m/z for all of the reagents in reaction with the (A6 3H)3 species.
For RNA 2′-O-transphosphorylation reactions, interactions with acid, base, or metal ion catalysts in solution can influence transition state structure. Understanding biological catalysis therefore requires knowledge of chemical mechanisms, transition state structure, and transition state interactions for both enzymatic and nonenzymatic RNA.
Transition Metals can be defined as a group of elements in the periodic table that are located at the center of the table including columns 3 through They include metals like copper, titanium, silver, platinum, nickel etc. During CO 2 electroreduction (CO 2 R), the hydrogen evolution reaction (HER) is a competing reaction.
We present a combined experimental and theoretical investigation of the HER activity of transition metals under CO 2 R conditions. Experimental HER polarization curves were measured for six polycrystalline metal surfaces (Au, Ag, Cu, Ni, Pt, and Fe) in the presence of CO 2 gas.